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- SIS page: NMST531
- Schedule: officially on Tuesday 14:00 - 15:30 in classroom K11
- Language: materials in English, instructed in Czech (unless anybody requires English)
- Instructur e-mail: vavraj@karlin.mff.cuni.cz
- Lecture web page: http://www.karlin.mff.cuni.cz/~kulich/vyuka/cens/index.html
- Note: exercises will start on 2nd November (untill then, lectures will replace exercise classes)
- CORONAVIRUS We have to be ready for any potential government restrictions.
- Presence form:
- weekly exercise class on schedule,
- completing given homework assignments in pre-specified deadlines (usually a day before the next exercise),
- exercise class will be opened with discussion over previous homework,
- we will go through the materials for exercise class together,
- there will be time for you to ask questions, work on given assigments, …
- no attendance requirement for course credit.
- Distant form:
- regular self-study of given materials,
- completing given homework assignments in pre-specified deadlines,
- feedback and discussions over the last exercise and homework via ZOOM session shortly after the deadline,
- also in ZOOM: assignment of a new homework for the next week with a short commentary,
- not in ZOOM: full lecture and detailed exploration of given materials (everybody has his/her own pace while working with R).
Credit
- Satisfactory solution to given assignments by the prescribed deadline.
(If your solution will not be satisfactory enough, you might be asked for revision.)
Send your solution via email to address vavraj@karlin.mff.cuni.cz.
Recommended form: Rmarkdown output (PDF or HTML)
Overview
- HELD ON-LINE on 22nd November at 14:30!!! No exercise class on the next Tuesday in K11!!!
- Topic: Confidence intervals and bands for survival function
- Dataset: km_all.RData
- Assignment: Compute and plot [KM] estimates including Hall-Werner bands. Perform short (or long if you wish) simulation study.
- Deadline: Tuesday 30th November 9:00
Exercise 5 (30th November - 7th December)
- Topic: Testing equality of censored distributions
- Datasets: km_all.RData
- Assignment: Calculate and plot [KM], [NA] estimates and smoothed estimator of hazard function when differentiating different groups. Perform two-sample tests and decide (based on the plots) which test statistic would be the most appropriate.
- Deadline: Tuesday 7th December 9:00
- Topic: The choice of two-sample test statistic
- Datasets:
data(veteran)
, nurshome
- Assignment: Fill table of appropriateness of different weights in two-sample survival tests in different situations. Perform several real data analyses and simulation study.
- Deadline: Tuesday 14th December 9:00
Exercise 7 (14th December - 4th January)
- HELD ON-LINE on 14th December at 14:00!!! See e-mail for the ZOOM link.
- Topic: Building Cox models for censored data (constant covariates)
- Dataset:
pbc
dataset from library(survival)
- Assignment: Perform exploratory analysis focused on the influence of covariates on the survival probability. Build a reasonable Cox model (starting from simple univariate models). Compare your final Cox model to your final model from Exercise 1.
- Deadline: Tuesday 4th January 9:00
- HELD ON-LINE on 21st December at 14:00!!! See e-mail for the ZOOM link.
- Topic: Generalizations of the Cox model
- Dataset:
pbc
and cgd
datasets from library(survival)
- Assignment: None, just admire what else could be done with the Cox model.
- Topic: Time-varying covariates in the Cox model
- Dataset:
jasa
and heart
dataset from library(survival)
- Assignment: Try to reproduce
heart
dataset from jasa
. Build and interpret Cox model with covariate indicating the time of heart transplantation and other fixed covariates. Does transplantation help patients to survive longer? Plot estimated survival functions.
- Deadline: Tuesday 18th January 9:00