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- SIS page: NMST531
- Schedule: officially on Monday 12:20 -
13:50 in classroom K4
- Language: materials in English, instructed in Czech
(unless anybody requires English)
- Instructur e-mail: vavraj@karlin.mff.cuni.cz
- Lecture web page (from previous year): http://www.karlin.mff.cuni.cz/~kulich/vyuka/cens/index.html
- Note: exercises will
start by the end of October
(untill then, lectures will replace exercise classes)
- CORONAVIRUS We have to be
ready for any potential government restrictions.
- Presence form:
- weekly exercise class on schedule,
- completing given homework assignments in pre-specified deadlines
(usually a day before the next exercise),
- exercise class will be opened with discussion over previous
homework,
- we will go through the materials for exercise class together,
- there will be time for you to ask questions, work on given
assigments, …
- no attendance requirement for course credit.
- Distant form:
- regular self-study of given materials,
- completing given homework assignments in pre-specified
deadlines,
- feedback and discussions over the last exercise and homework via
ZOOM session shortly after the deadline,
- also in ZOOM: assignment of a new homework for the next week with a
short commentary,
- not in ZOOM: full lecture and detailed exploration
of given materials (everybody has his/her own pace while working with
R).
Credit
- Satisfactory solution to given assignments by the prescribed
deadline.
(If your solution will not be satisfactory enough, you
might be asked for revision.)
Send your solution via email to
address vavraj@karlin.mff.cuni.cz.
Recommended form:
Rmarkdown
output (PDF or HTML)
Overview
- Topic: Testing equality of
censored distributions
- Datasets: km_all.RData
- Assignment: Calculate and plot [KM], [NA] estimates
and smoothed estimator of hazard function when differentiating different
groups. Perform two-sample tests and decide (based on the plots) which
test statistic would be the most appropriate.
- Deadline: Tuesday 13th
December 9:00 (also for Ex 6!)
- HELD TOGETHER WITH Ex5 on 5th December at
12:20!
- Topic: The choice of two-sample test statistic
- Datasets:
data(veteran)
, nurshome
- Assignment: Fill table of appropriateness of
different weights in two-sample survival tests in different situations.
Perform several real data analyses and simulation study.
- Deadline: Tuesday 13th
December 9:00 (also for Ex 5!)
Exercise
7 (13th December - 2nd January)
- Held on Tuesday 13th December at 14:00!!!
On Monday 12th December there will be a lecture on Cox model by doc.
Hlubinka.
- Topic: Building
Cox models for censored data (constant covariates)
- Dataset:
pbc
dataset from
library(survival)
- Assignment: Perform exploratory analysis focused on
the influence of covariates on the survival probability. Build a
reasonable Cox model (starting from simple univariate models). Compare
your final Cox model to your final model from Exercise
1.
- Deadline: Monday 2nd
January 9:00
- Topic: Generalizations of the Cox
model
- Dataset:
pbc
and cgd
datasets from library(survival)
- Assignment: None, just admire what else could be
done with the Cox model.
- Topic: Time-varying covariates
in the Cox model
- Dataset:
jasa
and heart
dataset from library(survival)
- Assignment: Try to reproduce
heart
dataset from jasa
. Build and interpret Cox model with
covariate indicating the time of heart transplantation and other fixed
covariates. Does transplantation help patients to survive longer? Plot
estimated survival functions.
- Deadline: Monday 16th
January 9:00